- Habitually aborting Angora doe. 4. Adrenal function in normal and aborter does
|Last update: April 3, 2012 03:23:33 PM|
THE HABITUALLY ABORTING ANGORA DOE. IV. ADRENAL FUNCTION IN NORMAL AND ABORTER DOES
D. WENTZEL, J. C. MORGENTHAL and C. H. VAN NIEKERK
Plasma corticosteroid concentration was determined by competitive protein binding assay (CPB) in normal and aborter Angora goat does and foetuses. Circulating corticosteroids increased between days 30 and 50 of pregnancy in normal does and then maintained a relatively high level of nearly 10 ng/ml plasma until the 90th day of gestation. This was followed by a progressive decline to 3 ng/ml at 120 days which was maintained up to parturition.
Corticosteroid concentration in aborters which expelled apparently normal fresh foetuses resembled that of normal does. Adrenal function in the foetuses of these animals also appeared to be normal.
The corticosteroid level in aborters whose foetuses had died in an oedematous state in utero was abnormally high throughout the gestational period preceding foetal death. Indications of adrenal hyperactivity were also evident in abortuses of these does.
Does whose kids had died perinatally, displayed anomalously high corticosteroid levels during the last third of gestation.
Plasma corticosteroid levels showed a sharp preparturient increase in normal foetuses.